Alberta rancher heading to California to help horses displaced by wildfire

first_imgOLDS, Alta. — A retired Alberta rancher is getting ready for a long trip to help hundreds of horses that have been displaced by wildfires in California.Darrell Glover says when he saw news reports about the destructive fires he knew he needed to do something for the animals that have suffered because of the disaster.He says horse owners who were forced to flee the flames couldn’t take their horses with them, so they let them go fend for themselves.Glover is planning to haul more than 6,300 kilograms of donated feed to a California ranch that is looking after the displaced animals.“As a horse owner, that created some emotional moments for us, so we started thinking that with all those horses, and there are hundreds of them running free in the hills … somebody had to help and try and feed these horses,” he said from his rural property north of Olds.Glover is also taking donated tack and medical supplies.His destination is the Camelot Equestrian Park in Orville, Calif.“They had the fire just about 100 metres from their front gate, so they almost lost their place as well,” said Glover.“Those folks have taken in a couple hundred horses so what we’re going to do is take down this trailer load of feed and help them out.”Glover said he wants to help all he can, especially because everyone in the region has lost so much.The Camelot Equestrian Park Foundation knows Glover is coming.“To Darrell Glover and all our Canadian Friends, there are no adequate words to express our gratitude for all of your compassion and generosity,” the Foundation said on Facebook.“It is awe inspiring that our neighbours to the north are willing to put this very special delivery together.”Glover said he plans to start heading south to California on Monday. (CTV Calgary)  The Canadian Presslast_img read more

Read More →

Four Mounties sue attorney general over 2014 Moncton shootings

first_imgMONCTON, N.B. — Four RCMP officers who responded to the 2014 shootings in Moncton, N.B.,  that claimed the lives of three of their colleagues are suing the attorney general of Canada for negligence.Mathieu Daigle, Martine Benoit, Robert Nickerson and Shelly Mitchell say in the filings they were inadequately trained and outfitted to deal with a heavily armed shooter on June 4, 2014.In motions filed with the Court of Queens Bench dated last week, the four say they suffer from post-traumatic stress disorder and other ailments and are seeking damages to be determined by the court.The four say a Sept. 29, 2017 conviction of the RCMP on Labour Code charges made clear that the RCMP did not act with due diligence in the rollout of carbines for members, putting their lives at risk.In that ruling, Judge Leslie Jackson found the force guilty of failing to provide its members with the appropriate use-of-force equipment and user training when responding to an active threat or active shooter in an open environment.Constables Fabrice Gevaudan, Dave Ross and Doug Larche were killed, while constables Eric Dubois and Darlene Goguen were wounded when Justin Bourque targeted police officers in hopes of sparking an anti-government rebellion.Bourque was given three consecutive life sentences without chance of parole for at least 75 years.The Canadian Presslast_img read more

Read More →

Aboriginal child almost abducted Mommy someone tried to take me

first_imgAPTN National NewsA 13-year-old First Nation girl was walking home after visiting friends in downtown Whitehorse Monday when she says someone tried to abduct her in a back alley behind a mall.“When she called me she was very frantic on the phone and all she could say was ‘mommy somebody tried to take me,’” said the girl’s mom Jennifer Mitchell.The girls says she was approached by a man driving a grey or turquoise sedan. He stopped, reached out and tried to grab her and pull her into the vehicle, but she took off down a road.She says he followed her for another three blocks and he finally left her alone after she pulled out her phone to call for help.“He kept telling her to come to the car and he just reached out and just missed grabbing her,” said Mitchell.The suspect is not known to the victim and the RCMP are investigating.“At this stage were looking for more information, but what we do have is that he was reportedly driving a new model sedan so a four-door vehicle either grey or turquoise in colour,” said Const. Julie Fox. “He’s older. Has a dark complexion, white beard and at the time was wearing tanned colored baggy clothing.”APTN’s Shirley McLean said there’s another report of the same man trying to abduct a different young woman on the same day.last_img read more

Read More →

Ford recalls almost 14M cars steering wheel can come loose

first_imgDETROIT – Under pressure from U.S. regulators, Ford is recalling nearly 1.4 million midsize cars in North America — including 62,479 in Canada — because the steering wheels can detach from the steering column and drivers could lose control.The recall covers certain Ford Fusion and Lincoln MKZ cars from the 2014 through 2018 model years.Ford says steering wheel bolts can loosen over time. The company says it knows of two crashes and one injury caused by the problem.Dealers will replace the bolts with longer ones that have more aggressive threads and a nylon patch to stop them from coming loose. Owners will be notified by mail the week of April 30, and parts are expected to be available by then.Just over 1.3 million cars in the U.S. are being recalled, with the rest in Canada and Mexico.The recall comes about five months after the U.S. National Highway Traffic Safety Administration opened an investigation into steering wheels falling off of Fusions from the 2014 through 2016 model years.The safety agency said in documents that it began the probe after receiving three complaints, including one from a driver from Georgia who reported that the steering wheel in a 2015 Fusion fell into their lap when turning into a gas station.Two other people reported that the bolt attaching the wheel to the steering column came loose while driving and had to be retightened at a repair shop. At the time the agency had no reports of crashes or injuries.Ford isn’t the only manufacturer to issue a recall for steering wheels coming off. In February, Hyundai recalled 43,900 vehicles which were at risk of the steering wheel breaking away from the steering column. That recall affected the 2018 Santa Fe and Santa Fe Sport SUVs.last_img read more

Read More →

President Lightstone recognizes Brock faculty and staff at annual Holiday celebration

Five individuals were recognized by 35 years of service to Brock:Ed Blasinski – Director: Project and Administrative Support OfficeRichard Brown – Associate Professor: PhilosophyBarry Grant – Professor: CommunicationsDonna Grant – Manager: Librarian’s OfficeDavid Siegel – Professor: Political ScienceJoining the 25-year club this year were:Anne Adams – Library AssistantBarbara Alexander – Administrative Assistant: Tourism ManagementTom Arkell – AVP – University ServicesPamela Barkwell – Co-ordinator ReadingMarisa Battista – Administrative Assistant: AccountingCharles Burton – Associate Professor: Political ScienceSusan Drake – Professor: Faculty of EducationNancy Francis – Professor: KinesiologyFrank Fueten – Professor: Earth SciencesGloria Gallagher – Associate RegistrarEugene Kaciak – Professor: FinanceJozef Kamendy – Custodial and Ground ServicesPeter Landey – Associate Professor: MusicAnna Lathrop – Vice-Provost, Teaching and LearningDave MacIntyre – Custodial and Ground ServicesLesa Mansfield – Administrative Co-ordinator: Teacher EducationSharon Mason – Associate Professor: Organizational Behaviour, Human Resources, Entrepreneurship and EthicsKen McClelland – Trades Helper: Maintenance and Utility ServicesJoffre Mercier – AVP- ResearchRico Natale – Director: Student Awards and Financial AidLinda Pidduck – Administrative Assistant: PsychologySandra Regier – Administrative Assistant: Faculty of EducationJohn Sainsbury – Professor: History DepartmentChris Tatarnic – Microcomputer Analyst: Client ServicesNorm Witteveen – Custodial and Ground ServicesAlso at the event, five members of the Brock community received the President’s 2014 Distinguished Staff Awards:Caroline Barrow – Biological SciencesGrant Myers – Custodial and Ground ServicesCarol Penner – Child and Youth StudiesMargaret Thompson – Office of the University SecretaryPhilip Thomas – Office of Research Services Brock University President Jack Lightstone capped off his annual holiday celebration by recognizing several outstanding faculty and staff members Monday afternoon at Pond Inlet.A total of 30 people were honoured in 2014, joining 165 other faculty and staff who have dedicated at least a quarter century of service to Brock.Lightstone also presented five individuals with Distinguished Staff Awards. read more

Read More →

Logan Stieber named Big Ten Male Athlete of the Year

Ohio State’s Logan Stieber reacts after winning his fourth consecutive NCAA title by beating Edinboro’s Mitchell Port in the 141-pound championship match during the NCAA Division I Wrestling Championships on March 21, 2015, at the Scottrade Center in St. Louis.Credit: Courtesy of TNSAfter winning his fourth individual national championship in as many years and helping the Ohio State wrestling team to its first-ever team championship, Logan Stieber was named the Big Ten Jesse Owens Male Athlete of the Year on Wednesday morning.Stieber, who ended his collegiate career on a 50-match winning streak dating back to December 2013, was the first wrestler in Big Ten history to complete a perfect 4-for-4 individual championship career, and just the fourth college wrestler to ever pull off the feat. He won the Dan Hodge Trophy as the nation’s top wrestler for his senior season, the first recipient in OSU history.“Logan is a special student-athlete who has left a legacy at Ohio State,” OSU wrestling coach Tom Ryan said in a press release. “His four national titles are the first ever for a Big Ten athlete, but it was his ability to lead the program to our first-ever NCAA team title that most accurately defines him. I am proud that someone who has worked as hard as he has for as long as he has is receiving such great recognition.”Wrestling in the 141-pound weight class, the Monroeville, Ohio, native is the fourth OSU athlete to win Male Athlete of the Year honors, following basketball’s Evan Turner in 2010, gymnast Blaine Wilson in 1997 and football’s Eddie George the year prior.A fellow national champion, rowing’s Ashley Bauer, was OSU’s nominee for Female Athlete of the Year honors. However, the award went to Maryland junior lacrosse player Taylor Cummings, who was named Most Outstanding Player of the championship for the national champion Terrapins.Three former OSU athletes have won Female Athlete of the Year accolades: track and field’s Christina Manning in 2012, basketball’s Jessica Davenport in 2007 and volleyball’s Laura Davis in 1995.The award was first issued in 1982 for male athletes, with the honor for females being added a year later.Stieber also saw his name announced Wednesday as a nominee for Best Male College Athlete at ESPN’s 2015 ESPY Awards. Stieber is one of three OSU nominees at the ESPYs, alongside redshirt junior quarterback Cardale Jones for Best Breakthrough Athlete and football coach Urban Meyer for Best Coach/Manager.The ESPY Awards, which can be voted for on ESPN’s website, will be announced live on July 15 at 8 p.m. read more

Read More →

He had big eyes and looked straight at me Familys home ransacked

first_img“I tried to shoo him away, but he just hissed back at me every time. He was very aggressive.”I called Katherine, because I thought she might be able to help, but I think if anything she was just terrified that this creature was messing around with her clothes.”It was at that point that Caroline woke up, but she was too scared to really help. He was very hyperactive, jumping on door handles and making a lot of noise.”It was terrifying, because he moved so slowly. You could never tell whether he was about to attack, or if he was just scared. The animal “terrorised” the account manager’s home, eating a Nutri-Grain barCredit:Marek Chapanionek / SWNS.com “Eventually he took out a Nutri-Grain bar, and rushed into Katherine’s bedroom. Then he started rummaging around in the drawers, pulling out clothes and making a mess. He added: “I had to work from home – I think my boss was quite confused when I explained it all to him.”The man from the RSPCA said in his 29 years working there he had never seen a raccoon in someone’s house before. It was scary, and he caused a mess, but I miss him now that he’s gone.”He was a wonderfully curious creature, but I don’t think we could have a raccoon and a cat at the same time.” “We thought he must have been someone’s pet because he seemed to know how to open doors. He was an incredibly inquisitive creature, and kept on following me.”I decided to lead him downstairs and into Dotty’s cat-bed, where he settled in. I threw a washing basket over his head, but he quickly got it off and wasn’t too happy.”I tempted him into the cat box, and locked the cage door, so that he couldn’t get out this time.”The RSPCA weren’t available when I phoned, and when I dialled 101 they told me I could let him out – but I know that they can damage other wildlife, so I didn’t want to do that.”I tried to go to sleep, but he kept on crying out and making a racket. It was a difficult night, and one that I certainly won’t forget.”It is not known where the creature came from, but Mr Chapanionek believes it could only have entered the house through the cat-flap. Mr Chapanionek even called daughter Katherine, 19, who is a second-year politics student at the University of Reading, as the creature rummaged through her bedroom drawers.Eventually the unwelcome guest settled down in Dotty’s cage, allowing Caroline, a midwife at Northampton General Hospital, to get some sleep.Mr Chapanionek, of Horton, Northants, then called the RSPCA, who collected the raccoon at around 10am on Tuesday morning. Marek Chapanionek and Caroline Chapanionek, whose house was visited by a raccooncenter_img Marek Chapanionek and Caroline Chapanionek, whose house was visited by a raccoonCredit: Aaron Chown / SWNS.com The animal "terrorised" the account manager's home, eating a Nutri-Grain bar He said: “I was just finishing off defrosting the freezer when it happened, I was just about to head up to bed, as Caroline had already gone to sleep.”I heard some banging upstairs, and just assumed it was Dotty messing around. But then I heard her run down the stairs, and straight out the cat-flap.”I went upstairs, and noticed that the draw to Katherine’s bedroom was slightly open, which made me suspicious. Then I saw him, this shady creature, sat in the hallway.”He was looking through my wife’s bag, which she’d left out there. It was very frightening. He had these big eyes, and was looking straight at me. A couple’s family home has been ransacked by a raccoon after it crawled in through their cat-flap.Father-of-one Marek Chapanionek, 44, was defrosting his freezer at around 11.30pm on Monday night when the woodland critter entered his house.The animal then “terrorised” the account manager’s property, eating a Nutri-Grain bar from the handbag of wife Caroline, 47, and terrifying two-year-old cat Dotty. Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings.last_img read more

Read More →

Yokogawa and CiDRA in distributor agreement

first_imgYokogawa Electric Corporation and CiDRA Corporate Services Inc. announce that they have entered into a distributor agreement. Yokogawa will sell CiDRA’s SONARtrac® range of flowmeters in the Southeast Asian markets of Malaysia, the Philippines, Singapore, Thailand, Vietnam, and Indonesia; the Middle Eastern markets of Bahrain, Egypt, Kuwait, Oman, Qatar, Saudi Arabia, and the UAE; and the Republic of Korea.Yokogawa Australia, Yokogawa New Zealand, and CiDRA have been successfully working together since 2014, so this agreement will now extend coverage to include Southeast Asia, the Middle East, and Korea.last_img

Read More →

Alingsas HK are the new Swedish champions

The new Swedish champions are Alingsas HK! The best Swedish squad in 2013/2014 beat Lugi HF 24:22 in the “big final” at Malmo Arena in front of 10.467 fans. They managed to turnover the match from 19:22 and with series 5:0 finish the match in big style.Alingsas HK will play at the VELUX EHF Champions League next season.Alingsås HK – Lugi HF 24-22 (11-12)Alingsås HK:   Johan Nilsson 6, Jesper Konradsson 5, Daniel Tellander 4, Max Darj 3, Pontus Johanssson 2, Markus Stegefelt 2 (2), Marcus Enström & Alexander Borgstedt båda 1.Lugi HF:  Johannes Hippe 5, Jakob Wickman-Modigh 4, Albin Tingsvall 4, Hampus Jildenbäck 4, Jonatan Leijonberg 2, Joacim Ernstsson, Anders Hallberg & Niklas Gudmundssson alla 1.Results: 1-3, 2-5, 5-6, 8-7, 9-11, 11-12 (paus), 13-13, 16-14, 16-18, 18-18, 18-21, 19-22, 24-22. Alingsas HKSweden ← Previous Story POLISH FINAL: Wisla VS Kielce 1:2! Next Story → PORTUGAL: FC Porto win sixth title in a row! read more

Read More →

Column Restoring the Christmas bonus should be a nobrainer

first_imgIT IS TIME for the Government to reinstate the Christmas Bonus, the once-off end of year payment for elderly people, carers and long-term social welfare recipients.The Labour Party was right, when in 2009 and in opposition, they said: “If the cancellation of the December social welfare bonus is approved, it will represent an outright attack on the most needy and the ‘savings’ will mean that people will be forced to go to money lenders as families struggle to get through what can be a tough time of year.”Four years on, it is time for the Government to look at this issue again. Put simply, the restoration of the Christmas bonus would be a huge boost for people who rely on social welfare payments and for the economy. The total cost of the restoration of the Christmas bonus would be €260 million. This money is likely to be spent mainly in the local economy, giving a valuable boost to domestic economic activity.The €260 million is a gross figure because it does not take account of the extra revenue that would be generated through VAT and Excise Duty receipts from people spending the bonus.A much-needed boostReinstating the Christmas bonus would mean a little bit more money toward Christmas presents for children. It would mean a few euro extra would be available for trips to local facilities and amenities. Furthermore, given that older people and those on low incomes are struggling to heat their homes at this time of year, the Christmas bonus would help pay for essential fuel costs.There are a number of ways to raise the additional revenue. Why not start at the top? Much more could be done to tackle tax evasion and white collar crime. I have pointed out on numerous occasions, that allowing the revenue commissioners to employ 125 additional staff would raise 95 million euro, according to the Government’s own figures.This ought be a no brainier. However, the Government’s rigid adherence to the public sector recruitment embargo is preventing them from taking action.Move against our tax exilesDespite years of talk, no action has been taken to move against our tax exiles, some of whom are the most powerful figures in the state. There are a number of ways to ta high earners more effectively. Some of the measures to more fairly tax higher income groups, such as a wealth tax, are long standing features of taxation policy elsewhere. A wealth tax, if applied along the lines for the French model, would raise 500 million euro, for example.I have had very few opportunities to agree with Minister Joan Burton in recent years. However, I do agree with what she said in April 2009 when she commented: “The Christmas bonus abolition is particularly mean-spirited and cutting welfare at a time of the year when people come under severe financial pressure will lead to people resorting to money lenders and high-interest loan providers.”The Labour Party should make good on its policies in opposition, which secured the support of so many people who actually voted for the party in 2011, and re-introduce the Christmas Bonus.Patrick Nulty is a TD for Dublin WestBurton: There’ll be no delay restoring Jobseeker payments for seasonal workersRead: €1 million deducted from social welfare benefits to pay property taxWe’re interested in your ideas and opinions – do you have a story you would like to see featured in Opinion & Insight? Email opinions@thejournal.ielast_img read more

Read More →

VetiGel instantly stops bleeding demoed in somewhat gruesome video

first_imgYou would think by this point in medical science we would have found the best way to stop bleeding, but a College Junior at New York University is spearheading research that might change the way wounds are cared for. Joe Landolina is working with senior researchers at Englewood Hospital in New Jersey to develop a substance called Veti-Gel, an easy to use compound that can stop bleeding almost instantly.Veti-Gel works by interacting with the extracellular matrix (ECM) in the human body. Believe it or not, you are not wall-to-wall cells. The collection of carbohydrates and fibrous proteins in the space in-between cells is the ECM. Veti-Gel is mainly composed of plant proteins that mimic the human ECM, allowing the gel to bind to existing tissues around a wound. Not only does the application of Veti-Gel act as a physical barrier to bleeding, it activates clotting factors from its interaction with the ECM to accelerate the body’s natural healing process.Early research on the substance is promising. Researchers have been able to stop bleeding in mice from internal liver injuries, and punctures to the carotid artery. There is also speculation that Veti-Gel could protect and heal burns. Human trials are still pending, but you can see Verti-Gel in action in the above video. A three-inch incision is made in a pig liver, then blood is pumped in. Veti-Gel stops the bleeding in a matter of seconds.Veti-Gel isn’t the only compound designed to seal up wounds. The US Army uses QuickClot gauze, and hospitals sometimes apply a gelatin-based substance called Floseal. Landolina’s project would have several notable advantages if it works in practice. First, it would be extremely easy to manufacture as it’s entirely plant-based. Additionally, Veti-Gel can be stored at room temperature.Landolina has filed a patent, and is applying for FDA approval. He hopes to receive a Department of Defense grant to help develop Veti-Gel into a real product.last_img read more

Read More →

Anonymous soutiendraient LulzSec

first_imgAnonymous soutiendraient LulzSecLe FBI aurait arrêté les leaders du groupe de hackers LulzSec, au début du mois de mars. Mais voilà qu’une vidéo, postée sur YouTube, laisse penser que ce groupe est toujours en activité.En effet, la vidéo annonce des actions prévues pour le 1er avril contre des entreprises ou encore des gouvernements: “Il y a quelques jours, nous avons décidé de ramener rapidement notre humble groupe de hackers…” annonce la voix, tout en précisant qu’il est “ridicule de croire qu’en arrêtant les six premiers membres de LulzSec…” l’activité allait se stopper nette.Cependant, la date choisie, célèbre pour son poisson d’avril notamment et les canulars qui vont avec, pourrait laisser croire qu’il s’agit là d’une blague. Des membres d’Anonymous tenteraient donc de démontrer que ce retour est bel et bien véridique en publiant un lien sur leur site, lié à LulzSec et au “Project Mayhem” (ancien projet ressortit visant des entreprises et gouvernement, qui prendrait place le 1er avril donc). Cela dit, les Anonymous n’en sont pas à leur premier coup d’essai en matière d’annonciation puis d’annulation d’évènement de ce genre.Mais nul doute que les autorités américaines sont sur le qui-vive, sachant de quoi sont capables ces groupes. Attendons maintenant le 1er avril pour savoir s’il s’agit là d’une simple farce où d’une véritable cyber attaque.Le 23 mars 2012 à 16:30 • Maxime Lambertlast_img read more

Read More →

Shelter Island boat launch reopened after refurbishment

first_imgShelter Island boat launch reopened after refurbishment 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek  . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSAN DIEGO (KUSI)- The busiest boat launch in California is officially back open. The shelter Island boat launch re-opened following a year and a half long refurbishing project.The $9.6 million project brought some improvements to the facility, including a new launch ramp, a public dock, and extra walkways. Posted: December 21, 2018 KUSI Newsroom, December 21, 2018 KUSI Newsroom Categories: Local San Diego News FacebookTwitterlast_img read more

Read More →

Lok Sabha 2019 Election guide Here is the full schedule and everything

first_imgThe EVMs have also been updated to the ‘M3’ third generation model for the 2019 Lok Sabha elections.The 2019 Lok Sabha elections will begin on April 11 and continue for over a month till May 19. The general elections will be held in seven phases. The counting of votes will take place on May 23 and results will likely be announced on the same day i.e. on May 23, according to Chief Election Commissioner Sunil Arora.Out of 90 crore voters eligible to vote, around 15 million voters are in the age group of 18-19 years. There will be approximately 10 lakh polling stations across the country as compared to 9 lakh polling stations in 2014. The 2019 general election will be the largest the world has seen.The Model Code of Conduct came into effect immediately after the announcement. The verifiable paper audit trail (VVPAT) will be used with EVMs at all polling stations in India. VVPAT will be making its national debut at the upcoming elections in India. However, the EVMs have also been upgraded for the 2019 LS elections to the ‘M3’ third generation models.The Election Commission of India gave out the schedule for 2019 Lok Sabha elections. Date of notificationMarch 19 Last date for withdrawal of candidatureApril 26 Date of notificationApril 2 Polling dateMay 19 Last date of filing nominationApril 4 Polling date April 11 Polling dateApril 23 Last date of filing nominationApril 29 Date of notificationApril 22 2April 18 Last date of filing nominationMarch 26 6May 12 3April 23 ResultMay 23 ResultMay 23 Date of notificationMarch 28 Scrutiny of nominationsApril 30 2019 Lok Sabha election: Phase IIThe Phase II of Lok Sabha polls will be held in 97 parliamentary constituencies spread across 13 states.Date of notificationDate of notificationMarch 19March 19Date of notificationLast date of filing nominationMarch 19March 26Date of notificationScrutiny of nominationsMarch 19March 27Date of notificationLast date for withdrawal of candidatureMarch 19March 29Date of notificationPolling dateMarch 19April 18Date of notificationResultMarch 19May 23 Last date for withdrawal of candidatureApril 12 ResultMay 23 Scrutiny of nominationsMarch 27 2019 Lok Sabha election: Phase IVThe Phase IV of Lok Sabha polls will be held in 71 parliamentary constituencies spread across nine states.Date of notificationDate of notificationApril 2April 2Date of notificationLast date of filing nominationApril 2April 9Date of notificationScrutiny of nominationsApril 2April 10Date of notificationLast date for withdrawal of candidatureApril 2April 12Date of notificationPolling dateApril 2April 29Date of notificationResultApril 2May 23 Polling dateApril 18 Last date for withdrawal of candidatureApril 8 2019 Lok Sabha election: Phase VIPhase VI of Lok Sabha polls will be held in 59 parliamentary constituencies spread across seven states.Date of notificationDate of notificationApril 16April 16Date of notificationLast date of filing nominationApril 16April 23Date of notificationScrutiny of nominationsApril 16April 24Date of notificationLast date for withdrawal of candidatureApril 16April 26Date of notificationPolling dateApril 16May 12Date of notificationResultApril 16May 23 Date of notificationMarch 18 Scrutiny of nominationsApril 20 ResultMay 23 Scrutiny of nominationsMarch 26 ResultMay 23center_img No assembly polls in J&KMeanwhile, the assembly elections in Jammu and Kashmir will not be held along with the Lok Sabha 2019 elections.2019 Lok Sabha election: Phase IThe Phase I of Lok Sabha polls will be held in 91 parliamentary constituencies spread across 20 states. Date of notificationDate of notificationMarch 18March 18Date of notificationLast date of filing nominationMarch 18March 25Date of notificationScrutiny of nominationsMarch 18March 26Date of notificationLast date for withdrawal of candidatureMarch 18March 28Date of notificationPolling dateMarch 18 April 11Date of notificationResultMarch 18 May 23 7May 19 Last date of filing nominationApril 18 Polling dateMay 12 Date of notificationApril 10 What is NOTA and how does it impact the elections?NOTA option is at the end of the list of candidates contesting in a constituency. The electors are free to use the negative ballot option. But, before opting for it, the voter needs to contact the presiding officer in a polling booth. The voter then has to cast their vote in a separate ballot paper and enter his/her name in a register. Earlier, the Supreme Court said this system was unconstitutional as it failed to protect the voter’s identity. The introduction of NOTA option in the voting machines does not require one should contact the presiding officer and it also helps maintain the anonymity of the voter casting it.Minimum criteria for votingA voter should be an Indian citizen.He/she must be 18 years and above.The elector should be a resident of a polling area of the Constituency.The voter must have a valid voter id card issued by the Election Commission of India.Election Commission joins TwitterThe ECI has joined Twitter to promote voter awareness ahead of the 2019 Lok Sabha elections. The account name, ECI #DeshKaMahaTyohar, will be used to make people aware of their voting rights. The EC’s decision to open a Twitter comes days after Twitter introduced an election emoji, which has an image of Parliament with hashtag available in 12 different languages.The Election Commission of India has also imposed strict limits on the expenditure incurred by candidates, not political parties, for their election campaigning. 2019 Lok Sabha election: Phase IIIThe Phase III of Lok Sabha polls will be held in 115 parliamentary constituencies spread across 14 states.Date of notificationDate of notificationMarch 28March 28Date of notificationLast date of filing nominationMarch 28April 4Date of notificationScrutiny of nominationsMarch 28April 5Date of notificationLast date for withdrawal of candidatureMarch 28April 8Date of notificationPolling dateMarch 28April 23Date of notificationResultMarch 28May 23 2019 Lok Sabha election: Phase VPhase V of Lok Sabha polls will be held in 51 parliamentary constituencies spread across seven states.Date of notificationDate of notificationApril 10April 10Date of notificationLast date of filing nominationApril 10April 18Date of notificationScrutiny of nominationsApril 10April 20Date of notificationLast date for withdrawal of candidatureApril 10April 22Date of notificationPolling dateApril 10May 6Date of notificationResultApril 10May 23 Scrutiny of nominationsApril 24 4April 29 The first phase of polling will be held on April 11, the second phase on April 18, third phase on April 23, fourth phase on April 29, fifth phase on May 6, sixth phase on May 12 and seventh phase on May 19 for 543 Lok Sabha seats across India.PhasesPhasesPolling DatesPolling DatesPhases1Polling DatesApril 11Phases2Polling DatesApril 18Phases3Polling DatesApril 23Phases4Polling DatesApril 29Phases5Polling DatesMay 6Phases6Polling DatesMay 12Phases7Polling DatesMay 19 Polling dateMay 6 Date of notificationApril 16 ResultMay 23 Last date for withdrawal of candidatureMarch 29 Last date for withdrawal of candidatureApril 22 Last date for withdrawal of candidatureMay 2 Scrutiny of nominationsApril 5 Last date of filing nominationApril 23 1April 11 2019 Lok Sabha election: Phase VIIPhase VII of the Lok Sabha polls will be held in 59 parliamentary constituencies spread across eight states.Date of notificationDate of notificationApril 22April 22Date of notificationLast date of filing nominationApril 22April 29Date of notificationScrutiny of nominationsApril 22April 30Date of notificationLast date for withdrawal of candidatureApril 22May 2Date of notificationPolling dateApril 22May 19Date of notificationResultApril 22May 23 Last date for withdrawal of candidatureMarch 28 PhasesPolling Dates Result May 23 Last date of filing nominationMarch 25 Scrutiny of nominationsApril 10 Polling dateApril 29 5May 6 Last date of filing nominationApril 9last_img read more

Read More →

After Trumps Win Some Texas Republicans Want the GOP To Be More

first_img Share MIGUEL GUTIERREZ JR. / KUTTrump supporters inside the Travis County Expo Center on August 23, 2016.Despite the results of this year’s election, there are still Republicans who say the party needs to appeal to a more diverse group of voters if they want to win the White House in the future. Specifically, they say the party needs to attract Hispanic voters.And the case study some Republicans are pointing to when they make this argument is solidly-red Texas.It was not too long ago that this argument was considerably easier to make.Right after President Obama was reelected in 2012, Republicans began taking stock. The lesson then-RNC Chair Reince Priebus learned was that the GOP needed to be more inclusive. Priebus appeared on MSNBC’s “Morning Joe” during that time. The show’s host, Joe Scarborough, asked him about members of the party who had issues with this strategy.“How do we take control as a party and make sure those voices are the voices of the minority, and that we embrace a bigger tent?” Scarborough asked.LISTEN: After Trump’s Win, Some Texas Republicans Want the GOP To Be More Inclusive KUT reports“Well, you’ve gotta make Reagan’s 80-20 rule cool again,” Priebus responded. “And that’s not just that my 80-percent friend is not my 20-percent enemy. And that we are not going to grow our party by division and subtraction.”Cut to 2016. The right flank of the GOP, and mostly white voters, propelled President-Elect Donald Trump to the White House and Priebus is set to become Trump’s chief of staff.To many people who still feel the GOP needs to be more inclusive, this election has brought up a lot of concerns.“I think the wrong lesson to learn from this election is that the Republican Party can rely on an overwhelmingly white electorate to win future national elections,” said Brendan Steinhauser, a Republican consultant in Texas who’s helped Republicans like Sen. John Cornyn win statewide elections.Part of his strategy has always been that “big tent” strategy –that is, keep the party relevant and don’t exclude and vilify minority voters.Steinhauser admits that, yes, Trump won by doing the opposite, but he says this will eventually stop working.“I think that this election in 2016, on a national level, was probably the last election where Republicans could rely on overwhelmingly white voters to win a national election,” he said.There’s evidence that this is already a problem for the GOP, and that evidence is Texas.Artemio Muniz, the president of the Federation of Hispanic Republicans, says not only did Trump get 1.2 million fewer votes this year in Texas compared to Mitt Romney in 2012, but things changed on a local level, as well.“We lost Harris County, which is Houston,” Muniz said. “We went from losing by about 600 votes in 2012 during the Obama wave, to now losing by about 160,000 votes. We saw an increase of about 34 percent of the Hispanic vote.”Muniz says big urban centers in Texas are the warning shot. The problem, he says, is that GOP leaders are still riding high on their big national wins this month.“But I am looking at the future,” Muniz said. “I am looking at 2020 as the year that the Hispanic community is becoming the plurality in Texas. And, if you look at the numbers in Dallas and Harris County and other counties, there was a huge representation by the Democratic turnout by the Hispanic community.”Muniz says he worries this trend could continue not just in Texas, but in Nevada, Colorado and Arizona, too. Down the road, he says, that could keep the White House out of reach for Republicans for a long time.Copyright 2016 KUT-FM. To see more, visit KUT-FM.last_img read more

Read More →

HDHomerun Pulls Plug on TV Streaming Service Following Hollywood Lawsuit

first_img Popular on Variety ×Actors Reveal Their Favorite Disney PrincessesSeveral actors, like Daisy Ridley, Awkwafina, Jeff Goldblum and Gina Rodriguez, reveal their favorite Disney princesses. Rapunzel, Mulan, Ariel,Tiana, Sleeping Beauty and Jasmine all got some love from the Disney stars.More VideosVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9Next UpJennifer Lopez Shares How She Became a Mogul04:350.5x1x1.25×1.5x2xLive00:0002:1502:15 SiliconDust, maker of the HDHomerun connected TV tuners, is getting out of the pay TV business, at least for now: The company has informed its users that it is shutting down its Premium TV service over the next 30 days. The news comes after major Hollywood studios had sued the company supplying SiliconDust with TV programming.“We are writing to inform you that we will be ending the HDHomerun Premium TV service over the course of the next 30 days,” the company said in its email to customers, which was first reported by Cord Cutters News. “All individuals currently subscribed to Premium TV will be able to continue their service until their current month of service has concluded, at which time service will not be renewed.”HDHomeRun Premium TV offered paying subscribers access to 45 channels, including ESPN, CNN, Fox News and TNT, for $34 a month. The company began testing the service last summer, and officially rolled it out later in 2018. Unlike some of the other TV subscription packages, Premium TV also allowed consumers to record shows locally, which made it easier to skip ads.center_img The problem for SiliconDust was that Premium TV was powered by Omniverse One World Television, a company that recently got sued by major Hollywood studios for alleged copyright infringement. Omniverse has defended itself by claiming that it obtained a far-reaching license to redistribute satellite TV programming over the internet, but the lawsuit put the future of services powered by the company in doubt.SiliconDust didn’t immediately respond to a request for comment Friday, but the company has made it clear to customers that the decision to shut down Premium TV isn’t affecting its core business.“We want to thank you for your business, and we want to assure you that we are not done innovating,” the company said in its email. “We are excited about upcoming plans for improving the cord cutting and cord shaving experiences.”last_img read more

Read More →

The Legend of Zelda A Link Between Worlds breathes fun new life

first_imgThe formula for a game like The Legend of Zelda is not something you mess with. It’s a timeless classic that has proven so successful that releasing an HD remake of one of the Zelda titles was the biggest sales bump the Wii U had seen since launch day. Fortunately even within that unique formula there are elements that Eiji Aonuma and crew felt could be evolved, leading to a familiar gameplay experience with the right amount of tweaks to make things feel new.Firing up A Link Between Worlds will make Legend of Zelda fans feel right at home. The top-down 2D gameplay that made this series famous has only changed enough to introduce brighter colors and smoother animations. Otherwise, it’s very much what you expect to find in a Zelda game. Much of the animations for combat, picking up items, and interacting with people are enough to make you feel like you’re playing every other version of Zelda, but after a few minutes of wandering around it’s clear that things aren’t quite the way they used to be.In A Link Between Worlds you play host to a curious character named Ravio, who wears a purple cloak that mostly hides his face. Ravio gifts you with a bracelet that eventually allows you to flatten yourself against a wall like a living painting. This adds an almost 3D element to many of the puzzles in the game, but it can occasionally feel a little like Paper Mario. Ravio serves another purpose in the game as well, and it’s the most significant of the changes found in this title. Unlike previous games, Ravio is the keeper of many of the secondary tools and weapons you will use throughout the game.He starts off by gifting you with a bow with what seems like unlimited arrows for free. The bow has a power gauge that decreases every time you fire an arrow, but it replenishes fast enough that there’s never a problem having enough arrows to fire unless you’re truly careless. This same gauge is used for your magic, and since it replenishes on its own there’s no need to track down or fill your inventory with potions. This ultimately removes one of the more tedious parts of playing a Zelda game, and after a brief adjustment period it makes the more complicated puzzles a great deal more fun since you can actually focus on the puzzle.If you die at any point in the game, Ravio’s friend will fly by and pick the bow off of your body. This forces you to go back to get it from him, at which point he charges you a measly 10 rupees. This same thing happens over and over again as you find yourself in need of other items in the game. What’s cool about this particular setup is that you will eventually reach a point in the game where you can go get what you want from Ravio, instead of having the game hold your hand through the process of finding and using the tools. Some puzzles can be solved in multiple ways, so you can choose your favorite items for the job and do it your way.If you’re a Zelda fan it’s already plenty easy to get lost in one of the existing games for a few hours. What sets A Link Between Worlds apart is the added flexibility to play the game without most of the old inventory and hand holding game mechanics getting in the way. It makes playing the game for hours even easier, because you aren’t as likely to reach that point where you decide you’d rather take a break for the night instead of going back to stock up on everything and try again. It’s an fun ride, and a fantastic new way to look at playing Zelda titles.The Legend of Zelda: A Link Between Worlds will be available for $39.99 on the 3DS or part of the custom Zelda DS bundle due out this holiday season.last_img read more

Read More →

Scientists interpret physics behind invisibility cloaks

first_img Explore further A direct current (DC) remote cloak to hide arbitrary objects When a polarized plane wave is incident upon an ideal spherical cloak, the object behind the cloak is completely hidden, as shown in this figure (wave arrows from behind pass through the cloak to appear in front). Credit: Chen, et al. ©2007 PRL. “The cloak is both anisotropic and inhomogeneous: all of the components in the permittivity and permeability tensor are functions of the radius, which implies that the perfect invisibility cloak is very difficult to design,” Chen explained. “If we introduce a specific type of loss both in a spherical cloak and a cylindrical cloak, only the spherical cloak exhibits a zero backscattering, which indicates only the spherical cloak can still be rendered invisible with a monostatic (transmitter and receiver in the same location) detection. This is because the impedance of the spherical cloak is still matched to the free space in this particular loss case.”Because they have less stringent requirements, imperfect cloaks may offer a more realistic alternative for engineers. Although imperfect cloaks have non-zero scattering, the objects they cloak can still appear isolated from the outside field under certain specific conditions and the incident fields cannot penetrate into the hidden object. Besides, for an imperfect cloak with matched impedance, it can still be rendered invisible with monostatic detection, which is most widely used in current radar.“For a monostatic detection, no reflection wave will be received by the detector if the imperfect cloak has a matched impedance with the free space,” Chen explained. “Therefore, the imperfect cloak, even with its parameters deviated far from the ideal parameters, still can be made completely invisible with the monostatic detection as long as it satisfied the impedance requirement.”Since almost all current radars belong to the monostatic class, Chen explained that this research can offer a more realistic alternative for engineers. In the future, applications of invisible cloaks could include military uses such as making planes and weapons invisible to radar, enabling the possibility of looking out walls as if they were windows, and hiding ugly factories for aesthetic reasons.“The effectiveness of the cloak based on the analytical solutions of the electromagnetic wave interactions with metamaterial cloaks (ideal or non-ideal) can be quantitatively provided,” Chen said. “Our research work therefore provides a new way for the cloak design and to qualify the effectiveness or performance of a non-ideal cloak.”Citation: Chen, Hongsheng, Wu, Bae-Ian, Zhang, Baile, and Kong, Jin Au. “Electromagnetic Wave Interactions with a Metamaterial Cloak.” Physical Review Letters 99, 063903 (2007).Copyright 2007 PhysOrg.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of PhysOrg.com. Hongsheng Chen, Bae-Ian Wu, Baile Zhang, and Jin Au Kong have published their research on invisibility cloaks in a recent issue of Physical Review Letters. The group analytically demonstrated how electromagnetic waves interact with invisibility cloaks made of metamaterials, an interaction that is often different from conventional scattering with regular particles. Their findings will hopefully be useful for cloak design and applications, an exciting research area that is still in its early stages.“When an electromagnetic wave is incident onto a conventional sphere, part of the radiation will be scattered in all directions; while for a metamaterial cloak, the incident wave will smoothly pass through the cloak undeflected,” Chen explained to PhysOrg.com. “It is very interesting that a perfect metamaterial cloak shows no reflection or absorption but rather allows the Poynting power to bypass the hidden object. Our research also shows that the Poynting power inside of the cloak is not uniform: when close to the inner boundary of the cloak, the power flow density is close to zero, while near the outer boundary of the cloak, the power flow density becomes large.”The first invisible cloak made of metamaterials was created last year by Duke University researchers Shurig et al. Metamaterials, which are composed of a man-made matrix of tiny metal wires and loops that control electromagnetic waves, can create an area in space where no electromagnetic waves propagate. The light waves flow around the cloaked object like water in a creek flows around a rock, appearing on the other side in such a way that an observer can’t tell that the waves flowed around an obstacle. In the first experimental trial, the cloak hid the concealed object from the electromagnetic microwaves in two dimensions. Chen and his colleagues wanted to know if perfect invisibility could be achieved under any wavelength. The scientists explained that perfect invisibility is achieved when the scattering cross section is zero, which indicates that the cloak exhibits zero scattering. The group found that the parameters for a perfect cloak are very difficult to realize, and that when some specific type of loss is included, the three dimensional spherical cloak wrapped around a hidden object exhibits zero backscattering while a two dimensional cylindrical cloak does not.center_img Is a perfect invisible cloak theoretically possible? Are there certain wavelengths—such as those in the visible spectrum—that can’t be made invisible? How will using imperfect materials affect the performance of a cloak? Scientists from Zhejiang University and MIT have recently analyzed the physics behind invisibility cloaks in an attempt to answer some of these questions. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Scientists interpret physics behind invisibility cloaks (2007, August 22) retrieved 18 August 2019 from https://phys.org/news/2007-08-scientists-physics-invisibility-cloaks.htmllast_img read more

Read More →

Bone tissue engineering—nanoglue polymer membranes for robust bone regeneration

first_imgStep two: Surface characterization studiesSince bioactive membranes can integrate with surrounding osseous tissue (bone tissue), Deng et al. assessed the formation of bone apatite layers on the surface of biomaterials immersed in simulated body fluid (SBF) solution. After 7 days of immersion, the scientists observed clustered nodular aggregates on the PDA/PCL membranes, which increased dramatically by day 14. Comparatively, the control sample of pristine unmodified PCL retained Ca-P deposits at seven days, with islands of apatite by day 14. As the PDA content increased, therefore, the amount of apatite deposited on the surface increased. Deng et al. used the material characterization data to validate enhanced in vitro bioactivity of PDA/PCL membranes compared to the pure PCL control. Step three: Biofunctionalization studiesThe scientists assessed the cytocompatibility (cell biocompatibility) of the engineered PDA/PCL membranes relative to cell adhesion, spreading, and human mesenchymal stem cell (hMSCs) proliferation. The hMSCs largely exist in bone marrow to assist tissue repair during injury. After 6 hours of cell culture, the hMSCs with round cellular shapes did not adhere well on pure PCL but expressed filopodia for membrane surface attachment on three variants of PDA/PCL membranes. Using cell counting experiments and cell viability CCK-8 assays, Deng et al. showed that the content of PDA NPs significantly affected the number of viable cells attached on the surface, and observed optimal surface properties with the 2 percent PDA/PCL group in the work.The research team determined the optimal formula to engineer PDA/PCL membranes for guided bone tissue regeneration by determining the alkaline phosphatase (ALP) activity and calcium matrix production of hMSCs with Alizarin Red S (ARS) staining. Cell growth and osteogenic differentiation was low when the amounts of PDA NPs were either high or low, because low concentrations did not trigger cell growth, whereas high concentrations were toxic in the study. Since investigations at the molecular level are a powerful tool in biomaterials for bioengineering, Deng et al. investigated the interplay between hMSCs and engineered membranes using molecular tools. For this, they monitored the expression of osteogenesis-related genes ALP, Runx2, Col1a1 and OPN in hMSCs cultured on the membranes. At 7 days they observed substantial levels of ALP gene expression on the 2 percent PDA/PCL sample. By day 14, the level of Runx2 gene expressed on 1 and 2 percent PDA/PCL groups significantly outmatched the pure PCL group. However, by 21 days, the scientists did not observe a discernable difference among the four groups. They verified the observations using immunofluorescence staining and chose the 2 percent PDA/PCL membranes for optimal induction of hMSCs to differentiate into mature osteoblasts. Step four: Translational study Guided by the data from in vitro experiments, Deng et al. investigated the in vivo biofunctionality of the microfibrous membrane using an animal model. For this, they created critical-sized bone defects on mice skulls and placed fibrous membranes to cover the defects, followed by bone formation tests using micro-computed tomography (micro-CT), histological analyses and fluorescent labeling; four to eight weeks after implantation. When they examined the 3-D images of the micro-CT skulls, the 2 percent PDA/PCL membrane offered the largest areas of new bone formation, with considerable expansion to the center of the bone defect. The scientists obtained a higher content of calcified matrix and bone remodeling in the 2 percent PDA/PCL membranes for phenomenal osteoconductive integration. The team incubated the uncoated and coated membranes with stem cells isolated from bone marrow and implanted the membranes to regenerate skull bone defects in live mice. After a 2-month translational study, they revealed the ability of the sticky membranes to direct stem cells to produce significantly higher quantities of bone, compared with uncoated membranes. Bone defects and injuries can commonly occur at the microscopic level as congenital defects, due to accidents or as age-related degenerative disease. Most bone defects cannot be repaired spontaneously by self-healing mechanisms leading to an urgent requirement to develop robust biomaterials that facilitate bone repair in bone research and bone tissue engineering. Bioengineers can manipulate stem cell differentiation to form mature osteoblasts via guided tissue regeneration (GTR) on surface membranes for optimized, large-scale bone regeneration. In materials science and advanced functional materials, electrospun membranes have received massive attention for such guided tissue engineering strategies due to several biocompatible advantages, including:Biomimicry for stem cell attachmentLarge surface area to facilitate cell adhesion and growthThe ability to form 3-D fibrous membranes and accelerate the osteogenic potential of numerous stem cell lines (from mouse, rat and human species). Materials scientists classify synthetic GTR materials into two main categories as (1) bioabsorbable and (2) nonabsorbable materials; where nonabsorbable materials must be removed after implantation via a second surgery, causing increased healthcare expenses, while compromising newly generated tissue. In contrast, biodegradable membranes such as polyvinyl alcohol (PVA), poly (lactide-co-glycolide) (PLGA) or PCL are preferred for clinical implantations, although biological complications have seriously impeded their clinical adoption. In a new study now published on NPG Asia Materials, bioengineers report the development of a new fibrous membrane with stem cells to repair bone defects in the skulls of mice. For this, they incorporated mussel-inspired polydopamine protein as a promising compound to tether biological substances to the membrane surfaces, much like adhesive proteins in mussels. In the work, Yi Deng and a research team in the interdisciplinary departments of chemical engineering, mechanical engineering, materials technology, center for future materials and regenerative medicine in China and Australia, coated the biocompatible membranes with polydopamine nanoparticles to form many topological sites for calcium attachment and bone defect repair. More information: Yi Deng et al. Bioinspired and osteopromotive polydopamine nanoparticle-incorporated fibrous membranes for robust bone regeneration, NPG Asia Materials (2019). DOI: 10.1038/s41427-019-0139-5 Rabih O. Darouiche. Treatment of Infections Associated with Surgical Implants, New England Journal of Medicine (2004). DOI: 10.1056/NEJMra035415 Rajeswari Ravichandran et al. Precipitation of nanohydroxyapatite on PLLA/PBLG/Collagen nanofibrous structures for the differentiation of adipose derived stem cells to osteogenic lineage, Biomaterials (2011). DOI: 10.1016/j.biomaterials.2011.10.030 H. Lee et al. Mussel-Inspired Surface Chemistry for Multifunctional Coatings, Science (2007). DOI: 10.1126/science.1147241 TOP: Bone-like nodules formation. (a) SEM photographs of PDA/PCL fibrous membranes acquired after soaking in SBF for 7 and 14 days. (b) EDS data and Ca/P ratios of the particle sediments on the surface of PDA/PCL fibrous membranes at 14 days. BOTTOM: Cell attachment and proliferation. (a) SEM and b CLSM observation of adhering hMSCs on the engineered fibrous membranes with different PDA NP concentrations at 6 and 12 h. The red arrows in a point to the pseudopodia. The inserts in the upper right of (b) show the magnified images of a single cell. (c) Cell attachment and (d) proliferation curves of hMSCs on the sample surfaces obtained via CCK-8. * Represents p < 0.05 between groups, ** represents p < 0.01 between groups; and # represents p < 0.05 compared with other groups. Credit: NPG Asia Materials, doi: 10.1038/s41427-019-0139-5 TOP: Micro-morphologies of PDA NPs and electrospun PDA/PCL fibrous membranes. a TEM image of PDA NPs; b SEM images of the (b1) pristine PCL, (b2) 1% PDA/PCL, (b3) 2% PDA/PCL, (b4) 5% PDA/PCL, and (b5) 10% PDA/PCL fibrous membranes. The red arrows in b point to the filaments. BOTTOM: Chemical constituents of PDA/PCL fibrous membranes. (a) Raman spectra and (b) contact angles with corresponding water droplet images of PDA/PCL fibrous membranes. Credit: NPG Asia Materials, doi: 10.1038/s41427-019-0139-5 Journal information: New England Journal of Medicine New membrane class shown to regenerate tissue and bone, viable solution for periodontitis LEFT: In vivo evaluation of PDA/PCL fibrous membranes. (a) Reconstructed 3D micro-CT images of whole skulls after surgery at 8 weeks. (b) Quantification of new bone areas at 4 and 8 weeks. (c) Micro-CT images of the defects and d bone histomorphometry of membrane implants analyzed from the micro-CT data after 4 and 8 weeks. * represents p < 0.05 between groups, and & represents p < 0.05 compared with other groups. RIGHT: Histological and immunohistological analysis Histological and immunohistological analysis of the sections for calvarial defects only and defects implanted with PCL and 2% PDA/PCL fibrous membranes at 4 and 8 weeks post implantation: (a) H&E staining, (b) Masson staining, (c) toluidine blue staining, (d) and immunohistological staining of OCN. HB host bone; CT connective tissue; NB newly formed bone. The red arrows in a–c point to the blood vessel. Credit: NPG Asia Materials, doi: 10.1038/s41427-019-0139-5 The hematoxylin and eosin (H&E) staining revealed fibrous tissue in the cavities of the PCL group, with comparatively visible bone restructuring in the 2 percent PDA/PCL group. The scientists also observed bone with abundant vascularization after 8 weeks post-operation in the 2 percent PDA/PCL groups. They conducted further staining with Masson, toluidine blue and immunohistochemistry (IHC) staining to identify new bone and collagen formation in depth. The combined histological data revealed that employment of PDA NPs in engineered fibrous membranes significantly boost bone regeneration, supporting the hypothesis that in vitro osteodifferentiation was also effective in vivo. In this way, Yi Deng and co-workers bioengineered co-electrospun PDA NPs with a bioinert synthetic polymer to construct bioinspired, flexible and osteopromotive PDA/PCL fibrous membranes for bone tissue engineering applications in regenerative medicine. The amount of PDA NPs included in the composite significantly improved the chemical composition, fiber size and mechanical properties of the developed membranes. Both in vitro experiments and in vivo data validated the ability for new bone formation with 2 percent PDA/PCL constructs compared with pure PCL. The engineered PCL/PDA membranes are osteoconductive and easy to transplant with great potential for GTR applications. Explore further Osteogenic differentiation: a, b Coloration and quantification of ALP activity, c, d ARS staining and quantification of calcium production, and e RT-PCR analysis for osteo-specific genes on different PDA/PCL fibrous membranes. * represents p < 0.05 between groups, **represents p < 0.01 between groups. # represents p < 0.05 compared with other groups, and ## represents p < 0.05 compared with other groups. Credit: NPG Asia Materials, doi: 10.1038/s41427-019-0139-5 Citation: Bone tissue engineering—nano-glue polymer membranes for robust bone regeneration (2019, July 30) retrieved 18 August 2019 from https://phys.org/news/2019-07-bone-tissue-engineeringnano-glue-polymer-membranes.html , Biomaterials © 2019 Science X Network , Science In the present work, therefore, Deng et al. used the bioinspired adhesive protein secreted from mussels as a 'material-independent' and facile surface coating, engineering strategy based on catechol chemistry. Polydopamine (PDA) can facilitate osteoblastic differentiation of stem cells on a variety of substrates as a nanoscale biomaterials coating, to support mesenchymal stem cell attachment and induce reprogramming of human somatic cells. Nevertheless, PDA nanolayers can easily delaminate from surfaces to induce local cell apoptosis or inflammatory reactions as adverse effects. Deng et al. implemented specific experimental steps to overcome the existing limitations and develop a new biocompatible and biodegradable membrane in the lab. The newly engineered biomaterial or fibrous membrane will provide a favorable niche to steer the fates of local stem cells to form osteoblasts for bone regeneration. Step one: Engineering PDA-included PCL (PDA/PCL) with electrospinning The scientists used catechol chemistry for PDA/PCL fibrous membrane fabrication and synthesis. They uniformly dispersed the PDA nanoparticles (NPs) in PCL via continuous sonication and vortexing to form the fibrous membranes via electrospinning. Deng et al. used a scanning electron microscope (SEM) and observed surface properties of the random, micron-sized fibrous network. Comparatively, the pure PCL electrospun membranes remained smooth, whereas the integration of PDA NPs made the fiber surfaces rough. The scientists confirmed the new surface chemistry using Raman spectra and X-ray photoelectron spectroscopy (XPS) analysis. The biomaterials were hydrophilic allowing protein adsorption and cell attachment. The researchers conducted contact angle measurements to verify surface wettability and improved hydrophilicity after PDA modification compared to the pure, unmodified PCL membranes. Schematic drawing of the fabrication of the engineered membranes via electrospinning of PCL and PDA NPs. Credit: NPG Asia Materials, doi: 10.1038/s41427-019-0139-5 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

Read More →

Whats on Tap for Google at IO 2015

first_img Listen Now Problem Solvers with Jason Feifer May 27, 2015 Hear from business owners and CEOs who went through a crippling business problem and came out the other side bigger and stronger. We’re coming down to the wire now: Google I/O 2015 is just a few days away, and we’ll be liveblogging and reporting from the ground as soon as the festivities begin. Don’t let its reputation as a developer bonanza fool you, though. There’s going to be no shortage of workshops and code review sessions, but I/O is also where Google takes time to update its vision of the future for the people who will ultimately help build it. Of course, it’s not all starry-eyed speeches and technical breakdowns — this is, after all, the sort of show that featured a live streaming Google Hangout with four dudes who jumped out of a zeppelin. We can’t account for whatever crazy, spectacular bits the folks in Mountain View might be working on, but we do have a taste of what to expect when the show starts in earnest this Thursday.Android M comethAh, yes, and the meat and potatoes of any Google I/O. It shouldn’t come as a surprise that Google has moved to a mostly annual release schedule for big Android updates (something VP of Android Engineering Hiroshi Lockheimer brought up again in aninterview with Fast Company), which means we’ll get our first concrete sense of what Android M is like on Thursday morning. So far, the (rumored) changelog looks pretty promising. A recent BuzzFeed report suggests you’ll be able to get more mileage out of your fingerprints, for one — better support for biometric security has apparently been baked right into the OS, allowing users to log into apps with just a touch. This heightened focus on security and authentication also bodes well for some Android Pay announcements, too. First announced at MWC 2015, Google’s Android Pay platform aims to make it easier for app creators and stores to charge you for their wares via your Android phone. Senior Vice President Sundar Pichai was awfully light on Pay details in Spain (maybe it was the never-ending lure of jamón), but that shouldn’t be the case in San Francisco.Throw in some enhanced privacy controls that’ll let users more easily define what apps get to access what information and you’ve got yourself a pretty thoughtful update. Beyond that, Android Police claims Android M’s development has seen Google trying to improve RAM management and battery life so your phone runs smoother and lasts longer on a single charge. Lollipop’s Project Volta was a crucial step in this direction, but really, we’ll take all the performance improvements we can get.Google stepped out of its comfort zone by releasing a developer preview for Lollipop (née Android L) last year, and we strongly suspect they’ll do the same this year too. It’s basically a given that we’d be able to install whatever preview we’re given on the Nexus 6, but rumors of two new Nexus phones launching in 2015 have us hoping for a glimpse of some new hardware. The most recent spate of rumors suggest that we’ll get a pocket-friendly Nexus 5 sequel from LG with a 5.2-inch screen and a Snapdragon 808 chipset — same as in the mostly great LG G4 — as well as a 5.7-inch powerhouse from Huawei. No, really. LG’s a logical choice considering its close working relationship with the folks in Mountain View and Huawei has upped its Android game dramatically with devices like the P8 and Huawei Watch, but these things will almost certainly get their limelight at a standalone launch event.The war for your wristHonestly, we’re not expecting a ton of movement on the Wear front this week. After all, the platform just got a substantial upgrade a few weeks back, bringing WiFi support and some love-’em-or-hate-’em navigation gestures to your fancy wrist computers. Wear’s functionality might not see much in the way of upgrades, but I/O would be a great place for Google to announce iOS compatibility for its fleet of Android Wear watches. The feature’s been inching from rumor territory toward reality for months now — it was apparently almost done back in April — and we’ll be crossing our fingers all through the keynote for it.Prepare to have your ‘socks blown off’Image Credit: EngadgetJust about anything Google’s Advanced Technologies and Products division does makes headlines, and the outfit’s getting a primo slot on I/O day 2 to spill its secrets. Expect at least a brief update on Project Ara, as the modular phone makers inch ever closer to a test launch in Puerto Rico; if we’re lucky, we might even get a firm date for when those Ara-friendly food trucks take to the streets. We might not see many (or any) new Android Wear watches at I/O, but the ATAP team promises to show off a few new wearables on Friday, and if the tongue-in-cheek panel description is anything to go off, at least one of them is meant to get strapped to your lower extremities. In an age where smartwatches dominate the wearable conversation, is it finally time for a smart ankle watch? Erm, we’ll see. Also on deck is a new immersive Spotlight Story directed by Justin Lin (of Fast and Furious fame) that’s slated to debut “in full 360 with 3D soundsphere.”Speaking of 3D…Cardboard and BeyondLast year, the I/O swag bag came with a curious slab of cardboard that looked like it fell out of an IKEA box. That was Google Cardboard, an experiment in cheapo VR experiences that just might get fleshed out further this year. The Wall Street Journal reported earlier this year that the company is actively working to turn Android into a virtual reality operating system of sorts, and the I/O stage would be a fine place to put some speculation to rest. Let’s put pricey consumer VR headsets like those from Oculus and HTC aside — what better way to initiate the masses into alternate realms than with some awfully inexpensive gear?Thing is (as Gizmodo points out), Cardboard might not actually be made of cardboard anymore, and Google might push past the low-cost tidbits of virtual reality we’ve seen so far. Yeah, yeah, that’s nice and vague; there’s no denying Google’s dedicated to digging into alternate views to reality. Remember Project Tango, which put 3D-sensing cameras into tablets to give developers a taste of bringing software experiences into the world immediately around us? And its hefty investment in Magic Leap, a company that wants desperately to blur the line between the real world and ones powered by silicon? Regardless of what actually gets outed onstage, expect this to be the year Google starts taking VR really seriously.Connecting all the thingsImage Credit: EngadgetGoogle has a thing for not letting old, improperly executed ideas die. Google TV might have sunken into obscurity ages ago, but Android TV picked up where it left off… and is struggling to find its footing. The Nexus Player left us wanting when we first played with it and few OEMs have thrown their support behind the platform as a whole despite the neat tricks it brings to the table. There’s no way Google won’t spend time digging into the future of Android TV onstage, and it’s got at least one shiny, mostly new gadget to point to: NVIDIA’s Shield TV. The sleek set-top box was first outed at the 2015 Game Developers’ Conference, where it promised to blend Google’s search chops and broad app ecosystem with NVIDIA’s own graphics cards (for game streaming from your local Steam box) and cloud service (for game streaming from a server far, far away). Google’s got plenty of workshops slated for Cast-friendly apps, too, underscoring just how important devices like the Chromecast are to its plans in the living room. We wouldn’t hold our breath for new Chromecast hardware, but we’d be more than happy to be proven wrong on that one.Image Credit: EngadgetSpeaking of old ideas, reports of a service to succeed the ill-fated Android @Home project have been swirling like crazy. The Information reported last week that Google’s so-called Brillo software is meant to power seriously low-power devices (with as little as 32MB of RAM) and act as a sort of backbone for Internet of Things device makers to lean on. By providing the foundation for these early creators to build on, Google has a solid shot at creating a common platform with the potential to explode as homes and the things in them grow inexorably more connected. If we’re really lucky, Google will make it easy for companies to bake its first-rate voice input and search features into their wares too, although we’ll have to wait a few days before we find out.Then there’s Android Auto. Google pushed the in-car experience way hard at last year’s I/O, and since then we’ve seen it pop up in aftermarket head units from Pioneer and straight into new rides like the 2015 Hyundai Sonata. To say Android Auto is still in its early days is putting it pretty mildly — it doesn’t yet have the finesse and app support to make a seamless, obvious choice for most drivers — but expect Google to shed some light on how it’s doing and where else it’s going….And everything elseSome really important bits — like the future of Chrome, Chrome OS and how they’ll intersect — will certainly get their time onstage, but the scuttlebutt surrounding them in the days leading up to the show is usually pretty hushed. Expect to see Google push its flat, friendly Material Design even harder, too, as it’s long been said the look would eventually permeate the rest of its web properties. Remember, this is all just a taste of what Google’s got in store for us all this week. For more (you know you want it), just park it right there and keep your eyes peeled for all our dispatches from San Francisco starting this Thursday. 9 min read This story originally appeared on Engadgetlast_img read more

Read More →